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Article

Q beta RNA bacteriophage: mapping cis-acting elements within an RNA genome.

Journal of virology - 1 Aug 1990

Mills D R, Priano C, Merz P A, Binderow B D

Abstract excerpt

We have identified, for the first time, regions of cis-acting RNA elements within the bacteriophage Q beta replicase cistron by analyzing the infectivities of 76 replicase gene mutant phages in the presence of a helper replicase. Two separate classes of mutant Q beta phage genomes (35 different insertion mutants, each containing an insertion of 3 to 15 nucleotides within the replicase gene, and 41 deletion...

Topics

Base Sequence
Chromosome Deletion
Chromosome Mapping
Coliphages
DNA-Directed RNA Polymerases
Escherichia coli
Genes, Viral
Molecular Sequence Data
Mutation
Oligonucleotide Probes
Plasmids

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA Viruses

RNA, Viral

Restriction Mapping

Viral Plaque Assay

Source

Open in PubMed Open full text

Identifiers

PMID: 2196383
DOI: 10.1128/JVI.64.8.3872-3881.1990
PMCID: PMC249683

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2196383-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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