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Article

Solution structure of the pseudoknot of SRV-1 RNA, involved in ribosomal frameshifting.

Journal of molecular biology - 27 Jul 2001

Michiels P J, Versleijen A A, Verlaan P W, Pleij C W, Hilbers C W, Heus H A

Abstract excerpt

RNA pseudoknots play important roles in many biological processes. In the simian retrovirus type-1 (SRV-1) a pseudoknot together with a heptanucleotide slippery sequence are responsible for programmed ribosomal frameshifting, a translational recoding mechanism used to control expression of the Gag-Pol polyprotein from overlapping gag and pol open reading frames. Here we present the three-dimensional structure of...

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Identifiers

PMID: 11501999
DOI: 10.1006/jmbi.2001.4823
PMCID: PMC7172549

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Source receipt: pubmed, retrieved 7 Sept 2026.

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