Article
NMR structure of a classical pseudoknot: interplay of single- and double-stranded RNA.
Science (New York, N.Y.) - 17 Apr 1998
Kolk M H, van der Graaf M, Wijmenga S S, Pleij C W, Heus H A, Hilbers C W
Abstract excerpt
Pseudoknot formation folds the 3' ends of many plant viral genomic RNAs into structures that resemble transfer RNA in global folding and in their reactivity to transfer RNA-specific proteins. The solution structure of the pseudoknotted T arm and acceptor arm of the transfer RNA-like structure of turnip yellow mosaic virus (TYMV) was determined by nuclear magnetic resonance (NMR) spectroscopy. The molecule is...
Topics
- Amino Acyl-tRNA Synthetases
- Binding Sites
- Diethyl Pyrocarbonate
- Hydrogen Bonding
- Magnetic Resonance Spectroscopy
- Models, Molecular
- Mutation
- Nucleic Acid Conformation
- RNA, Double-Stranded
- RNA, Transfer