Article
Selection and characterization of RNAs replicated by Q beta replicase.
Biochemistry - 14 Nov 1995
Brown D, Gold L
Abstract excerpt
RNAs replicated by Q beta replicase were isolated from two random sequence RNA populations (one 56 nucleotides in length, the second 83) using a replication/dilution protocol. The selected molecules were cloned and sequenced, generating data set of 54 replicatable RNAs bound with higher affinity to Q beta replicase than did the random populations from which they were selected. Deletion analyses on two of the...
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