Selection and characterization of RNAs replicated by Q beta replicase.

doi:10.1021/bi00045a019

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Article

Selection and characterization of RNAs replicated by Q beta replicase.

Biochemistry - 14 Nov 1995

Brown D, Gold L

Abstract excerpt

RNAs replicated by Q beta replicase were isolated from two random sequence RNA populations (one 56 nucleotides in length, the second 83) using a replication/dilution protocol. The selected molecules were cloned and sequenced, generating data set of 54 replicatable RNAs bound with higher affinity...

Topics

Base Sequence
Binding Sites
Cloning, Molecular
Kinetics
Molecular Sequence Data
Mutation
Nucleic Acid Conformation
Oligoribonucleotides
Q beta Replicase
RNA
Sequence Analysis

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