Article
Local structural and environmental factors define the efficiency of an RNA pseudoknot involved in programmed ribosomal frameshift process.
The journal of physical chemistry. B - 16 Oct 2014
Gupta Asmita, Bansal Manju
Abstract excerpt
In programmed -1 ribosomal frameshift, an RNA pseudoknot stalls the ribosome at specific sequence and restarts translation in a new reading frame. A precise understanding of structural characteristics of these pseudoknots and their PRF inducing ability has not been clear to date. To investigate this phenomenon, we have studied various structural aspects of a -1 PRF inducing RNA pseudoknot from BWYV using...
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