Article
[The study of correlation between the K-ras genotype and murine susceptibility to chemically induced lung neoplasms].
Genetika - 1 Sept 1999
Timofeeva O A, Filipenko M L, Kaledin V I
Abstract excerpt
The susceptibility of the ICR, DD/He and CC57/BR mice to urethane-induced lung tumors was analyzed in comparison with the A/He (highly susceptible) and AKR (resistant) lines of mice. Allelic variants of the K-Ras gene intron 2 in these lines have been determined. Susceptibility of the ICR mice was similar to that of the A mice, and intron 2 of the K-Ras ICR gene carried the 37-bp deletion analogous to that...
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