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Article

The second intron of the K-ras gene contains regulatory elements associated with mouse lung tumor susceptibility.

Proceedings of the National Academy of Sciences of the United States of America - 15 Feb 1994

Chen B, Johanson L, Wiest J S, Anderson M W, You M

Abstract excerpt

We have previously demonstrated the preferential activation of the K-ras gene from the susceptible A/J parent in lung tumors from F1 mouse hybrids. In the present study, the mechanism of this observation is further investigated. Higher levels of expression of A/J K-ras allele were detected in lung adenomas (30 of 30) from the C3A mouse. In addition, three K-ras alleles, designated as susceptible (Ks),...

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Identifiers

PMID: 8108449
DOI: 10.1073/pnas.91.4.1589
PMCID: PMC43205

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The second intron of the K-ras gene contains regulatory elements associated with mouse lung tumor susceptibility.PMID 8108449Read ↗

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