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Article

Comparison of pulmonary O6-methylguanine DNA adduct levels and Ki-ras activation in lung tumors from resistant and susceptible mouse strains.

Molecular carcinogenesis - 1 Jan 1993

Devereux T R, Belinsky S A, Maronpot R R, White C M, Hegi M E, Patel A C, Foley J F, Greenwell A, Anderson M W

Abstract excerpt

The role of O6-methylguanine (O6MG) DNA adduct formation and persistence in the formation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced lung tumors from resistant C57BL/6 and susceptible A/J mice was investigated. In addition, the frequencies of pulmonary tumor formation and Ki-...

Topics

Animals
Base Sequence
DNA
Gene Expression
Genes, p53
Genes, ras
Guanine
Lung Neoplasms
Mice
Mice, Inbred A
Mice, Inbred C57BL
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Polymerase Chain Reaction

Source

Identifiers

PMID: 8216736
DOI: 10.1002/mc.2940080308

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8216736-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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