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Article

Different positioning elements select poly(A) sites at the 3'-end of GCN4 mRNA in the yeast Saccharomyces cerevisiae.

Nucleic acids research - 15 Dec 1999

Düvel K, Braus G H

Abstract excerpt

Cleavage and polyadenylation of eukaryotic mRNA requires efficiency and positioning elements in the 3'-untranslated region (3'-UTR) of the mRNA. Specific point mutations were introduced into the yeast GCN4 3'-UTR to detect sequence motifs which are involved in the positioning of the poly(A) site. 3'-End proces-sing activities of different GCN4 3'-UTR alleles were measured in an in vivo test system. Point...

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Identifiers

PMID: 10572175
DOI: 10.1093/nar/27.24.4751
PMCID: PMC148775

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