Article
Effect of RNA secondary structure on polyadenylation site selection.
Genes & development - 1 Jul 1991
Brown P H, Tiley L S, Cullen B R
Abstract excerpt
Functional polyadenylation [poly(A)] sites consist of two sequence elements, the AAUAAA and G/U box signals, that closely flank the site of mRNA 3'-end formation. In agreement with previous results, random sequence insertions between the AAUAAA and G/U box signals were observed to inhibit poly(A)...
Topics
- Animals
- Base Sequence
- Cell Line
- Chlorocebus aethiops
- Consensus Sequence
- Hydrolysis
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- Poly A
- RNA