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Article

RIα influences cellular proliferation in cancer cells by transporting RFC40 into the nucleus

1 Apr 2005

Abstract excerpt

The regulatory subunit (RIalpha) of cAMP-dependent Protein Kinase A (PKA) is overexpressed in a variety of tumors and carcinomas such as renal cell carcinomas, pituitary tumors of the rat, malignant osteoblasts, colon carcinomas, serous ovarian tumors and primary human breast carcinomas. However, the direct relation between overexpression of RIalpha and malignancy is still unclear. We have recently identified a...

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PMID: 15846072
DOI: 10.4161/cbt.4.4.1621

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