Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional roles for fatty acylated amino-terminal domains in subcellular localization.

Molecular biology of the cell - 1 Nov 1999

McCabe J B, Berthiaume L G

Abstract excerpt

Several membrane-associating signals, including covalently linked fatty acids, are found in various combinations at the N termini of signaling proteins. The function of these combinations was investigated by appending fatty acylated N-terminal sequences to green fluorescent protein (GFP). Myristoylated plus mono/dipalmitoylated GFP chimeras and a GFP chimera containing a myristoylated plus a polybasic domain were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acylation
Share to Calreticulin
Share to Golgi Apparatus

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Intracellular Membranes

Share to Luminescent Proteins

Share to Myristic Acid

Share to Palmitic Acids

Share to Ribonucleoproteins

Source

Open in PubMed Open full text

Identifiers

PMID: 10564270
DOI: 10.1091/mbc.10.11.3771
PMCID: PMC25678

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional roles for fatty acylated amino-terminal domains in subcellular localization.PMID 10564270Read ↗

N-terminal polybasic motifs are required for plasma membrane localization of Galpha(s) and Galpha(q).Semantic proximity Read ↗

Myristoylation is required for the intracellular localization and endocytic function of ARF6.Semantic proximity Read ↗

Docosahexaenoic acid selectively inhibits plasma membrane targeting of lipidated proteins.Semantic proximity Read ↗

Multiple sequence elements facilitate Chp Rho GTPase subcellular location, membrane association, and transforming activity.Semantic proximity Read ↗

The Palmitoylation Machinery Is a Spatially Organizing System for Peripheral Membrane ProteinsSemantic proximity Read ↗

Membrane targeting of L-type calcium channels. Role of palmitoylation in the subcellular localization of the beta2a subunit.Semantic proximity Read ↗

Novel determinants of H-Ras plasma membrane localization and transformation.Semantic proximity Read ↗

Depalmitoylated Ras traffics to and from the Golgi complex via a nonvesicular pathway.Semantic proximity Read ↗

Deletion of the regulatory domain of protein kinase C alpha exposes regions in the hinge and catalytic domains that mediate nuclear targeting.Semantic proximity Read ↗

The Activation of ARF1 Is Dynamically Regulated by its Palmitoylation.Semantic proximity Read ↗

Lack of palmitoylation redirects p59Hck from the plasma membrane to p61Hck-positive lysosomes.Semantic proximity Read ↗

CaaX-motif-adjacent residues influence G protein gamma (Gγ) prenylation under suboptimal conditions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.