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Article

Multiple sequence elements facilitate Chp Rho GTPase subcellular location, membrane association, and transforming activity.

Molecular biology of the cell - 1 Jul 2006

Chenette Emily J, Mitin Natalia Y, Der Channing J

Abstract excerpt

Cdc42 homologous protein (Chp) is a member of the Rho family of small GTPases and shares significant sequence and functional similarity with Cdc42. However, unlike classical Rho GTPases, we recently found that Chp depends on palmitoylation, rather than prenylation, for association with cellular membranes. Because palmitoylation alone is typically not sufficient to promote membrane association, we evaluated the...

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Identifiers

PMID: 16641371
DOI: 10.1091/mbc.e05-09-0896
PMCID: PMC1483044

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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