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Article

Novel determinants of H-Ras plasma membrane localization and transformation.

Oncogene - 7 Nov 1996

Willumsen B M, Cox A D, Solski P A, Der C J, Buss J E

Abstract excerpt

Although it is well-established that modification of Ras by farnesol is a critical step for its membrane association and transforming activity, the contribution of other C-terminal sequences and palmitate modification to Ras localization and function remains unclear. We have characterized H-Ras mutant proteins with alterations in the palmitoylated cysteines or in sequences flanking these residues. We found that...

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PMID: 8934536

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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