Article
Wingless signaling in the Drosophila embryo: zygotic requirements and the role of the frizzled genes.
Development (Cambridge, England) - 1 Feb 1999
Müller H A, Samanta R, Wieschaus E
Abstract excerpt
Wingless signaling plays a central role during epidermal patterning in Drosophila. We have analyzed zygotic requirements for Wingless signaling in the embryonic ectoderm by generating synthetic deficiencies that uncover more than 99% of the genome. We found no genes required for initial wingless expression, other than previously identified segmentation genes. In contrast, maintenance of wingless expression shows...
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