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Article

Frizzled and Dfrizzled-2 function as redundant receptors for Wingless during Drosophila embryonic development.

Development (Cambridge, England) - 1 Sept 1999

Bhanot P, Fish M, Jemison J A, Nusse R, Nathans J, Cadigan K M

Abstract excerpt

In cell culture assays, Frizzled and Dfrizzled2, two members of the Frizzled family of integral membrane proteins, are able to bind Wingless and transduce the Wingless signal. To address the role of these proteins in the intact organism and to explore the question of specificity of ligand-receptor interactions in vivo, we have conducted a genetic analysis of frizzled and Dfrizzled2 in the embryo. These...

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Source

Identifiers

PMID: 10457026
DOI: 10.1242/dev.126.18.4175

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Frizzled and Dfrizzled-2 function as redundant receptors for Wingless during Drosophila embryonic development.PMID 10457026Read ↗

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