Article
Meiotic interallelic conversion at the human minisatellite MS32 in yeast triggers recombination in several chromatids.
Gene - 18 Oct 1999
Appelgren H, Cederberg H, Rannug U
Abstract excerpt
Tandem repetitive DNA sequences such as minisatellites include the most polymorphic loci yet identified in the human genome. The high mutation rates at many of these loci are driven by incompletely understood recombination-based mechanisms that operate in the germline. To analyse aspects of minisatellite mutation processes and general eukaryotic recombination in meiosis that cannot be studied in humans or other...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
