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Article

Stimulation of gross chromosomal rearrangements by the human CEB1 and CEB25 minisatellites in Saccharomyces cerevisiae depends on G-quadruplexes or Cdc13.

PLoS genetics - 1 Jan 2012

Piazza Aurèle, Serero Alexandre, Boulé Jean-Baptiste, Legoix-Né Patricia, Lopes Judith, Nicolas Alain

Abstract excerpt

Genomes contain tandem repeats that are at risk of internal rearrangements and a threat to genome integrity. Here, we investigated the behavior of the human subtelomeric minisatellites HRAS1, CEB1, and CEB25 in Saccharomyces cerevisiae. In mitotically growing wild-type cells, these GC-rich tandem...

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Source

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Identifiers

PMID: 23133402
DOI: 10.1371/journal.pgen.1003033
PMCID: PMC3486850

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23133402-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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