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Article

Instability of the human minisatellite CEB1 in rad27Delta and dna2-1 replication-deficient yeast cells.

The EMBO journal - 17 Jun 2002

Lopes Judith, Debrauwère Hélène, Buard Jérôme, Nicolas Alain

Abstract excerpt

Convergent studies in human and yeast model systems have shown that some minisatellite loci are relatively stable in somatic cells but not in the germline, and little is known about the mechanism(s) that can destabilize them. Unlike microsatellite sequences, mini satellites are not destabilized by mismatch repair mutations. We report here that the absence of Rad27 and Dna2 functions but not RNase H(35) or Exo1,...

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Identifiers

PMID: 12065432
DOI: 10.1093/emboj/cdf310
PMCID: PMC125388

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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