Article
Mutation processes at human minisatellites.
Electrophoresis - 1 Sept 1995
Jeffreys A J, Allen M J, Armour J A, Collick A, Dubrova Y, Fretwell N, Guram T, Jobling M, May C A, Neil D L
Abstract excerpt
Minisatellites provide one of the most experimentally tractable systems for studying tandem repeat instability in man. Analysis of mutation processes has been greatly aided by the development of single molecule methods for recovering de novo mutants, and of techniques for exploring allele structure in detail. Application of these approaches to man has shown that minisatellites do not primarily mutate by processes...
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