Article
Influences of array size and homogeneity on minisatellite mutation.
The EMBO journal - 15 Jun 1998
Buard J, Bourdet A, Yardley J, Dubrova Y, Jeffreys A J
Abstract excerpt
Unstable minisatellites display high frequencies of spontaneous gain and loss of repeats in the human germline. Most length changes arise through complex recombination events including intra-allelic duplications/deletions and inter-allelic transfers of repeats. Definition of the factors modulatin...
Topics
- Alleles
- Humans
- Male
- Minisatellite Repeats
- Mutation
- Repetitive Sequences, Nucleic Acid
- Spermatozoa
