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Article

Somatic versus germline mutation processes at minisatellite CEB1 (D2S90) in humans and transgenic mice.

Genomics - 15 Apr 2000

Buard J, Collick A, Brown J, Jeffreys A J

Abstract excerpt

The most variable human minisatellites show extreme germline instability dominated by complex intra-allelic rearrangements plus a lower frequency of inter-allelic transfers of repeat units. In contrast, little is known about somatic instability at such loci. We have therefore used single-molecule PCR to analyze mutation at minisatellite CEB1 (D2S90) in human blood DNA. Somatic mutants were rare and involved only...

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Identifiers

PMID: 10783256
DOI: 10.1006/geno.2000.6161

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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