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Article

The Sch9 protein kinase regulates Hsp90 chaperone complex signal transduction activity in vivo.

The EMBO journal - 1 Nov 1999

Morano K A, Thiele D J

Abstract excerpt

Basal and stress-induced synthesis of the components of the highly conserved heat shock protein Hsp90 chaperone complex require the heat shock transcription factor (HSF); Saccharomyces cerevisiae cells expressing the HSF allele HSF(1-583) reversibly arrest growth at 37 degrees C in the G(2)/M phase of the cell cycle due to diminished expression of these components. A suppressor mutant capable of restoring...

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Identifiers

PMID: 10545107
DOI: 10.1093/emboj/18.21.5953
PMCID: PMC1171661

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Source receipt: pubmed, retrieved 7 Sept 2026.

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