Article
Identification of SSF1, CNS1, and HCH1 as multicopy suppressors of a Saccharomyces cerevisiae Hsp90 loss-of-function mutation.
Proceedings of the National Academy of Sciences of the United States of America - 16 Feb 1999
Nathan D F, Vos M H, Lindquist S
Abstract excerpt
Hsp90 functions in a multicomponent chaperone system to promote the maturation and maintenance of a diverse, but specific, set of target proteins that play key roles in the regulation of cell growth and development. To identify additional components of the Hsp90 chaperone system and its targets, we searched for multicopy suppressors of various temperature-sensitive mutations in the yeast Hsp90 gene, HSP82. Three...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
