Cns1 is an essential protein associated with the hsp90 chaperone complex in Saccharomyces cerevisiae that can restore cyclophilin 40-dependent functions in cpr7Delta cells.

doi:10.1128/MCB.18.12.7353

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Article

Cns1 is an essential protein associated with the hsp90 chaperone complex in Saccharomyces cerevisiae that can restore cyclophilin 40-dependent functions in cpr7Delta cells.

Molecular and cellular biology - 1 Dec 1998

Marsh J A, Kalton H M, Gaber R F

Abstract excerpt

Saccharomyces cerevisiae harbors two cyclophilin 40-type enzymes, Cpr6 and Cpr7, which are components of the Hsp90 molecular chaperone machinery. Cpr7 is required for normal growth and is required for maximal activity of heterologous Hsp90-dependent substrates, including glucocorticoid receptor (...

Topics

Amino Acid Sequence
Carrier Proteins
Cell Division
Peptidyl-Prolyl Isomerase F
Cyclophilins
Fungal Proteins
Gene Expression Regulation, Fungal
Genes, Suppressor
HSP90 Heat-Shock Proteins
Molecular Chaperones
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Peptidylprolyl Isomerase

Phenotype

Receptors, Glucocorticoid

Saccharomyces cerevisiae

Saccharomyces cerevisiae Proteins

Sequence Homology, Amino Acid

Source

Open in PubMed Open full text

Identifiers

PMID: 9819422
DOI: 10.1128/MCB.18.12.7353
PMCID: PMC109317

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9819422-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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