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Article

Functional and physical interaction between yeast Hsp90 and Hsp70.

Proceedings of the National Academy of Sciences of the United States of America - 6 Mar 2018

Kravats Andrea N, Hoskins Joel R, Reidy Michael, Johnson Jill L, Doyle Shannon M, Genest Olivier, Masison Daniel C, Wickner Sue

Abstract excerpt

Heat shock protein 90 (Hsp90) is a highly conserved ATP-dependent molecular chaperone that is essential in eukaryotes. It is required for the activation and stabilization of more than 200 client proteins, including many kinases and steroid hormone receptors involved in cell-signaling pathways. Hsp90 chaperone activity requires collaboration with a subset of the many Hsp90 cochaperones, including the Hsp70...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 29463764
DOI: 10.1073/pnas.1719969115
PMCID: PMC5877982

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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