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Article

Uncovering cellular circuitry controlling temperature-dependent fungal morphogenesis

1 Jul 2012

Abstract excerpt

Temperature change is a ubiquitous environmental signal, which exerts powerful control over the development and virulence of microbial pathogens. For Candida albicans, the leading fungal pathogen of humans, temperature influences mating, phenotypic switching, resistance to antifungal drugs and the morphogenetic transition from yeast to filamentous growth. C. albicans morphogenesis is profoundly influenced by...

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PMID: 22722238
DOI: 10.4161/viru.20979

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