Article
Spontaneous mutation frequency and pattern in Big Blue mice fed a vitamin E-supplemented diet.
Environmental and molecular mutagenesis - 1 Jan 1999
Moore S R, Hill K A, Heinmoller P W, Halangoda A, Kunishige M, Buettner V L, Graham K S, Sommer S S
Abstract excerpt
Endogenous oxidative DNA damage caused by normal cellular processes may play a vital role in carcinogenesis. To directly test the hypothesis that antioxidants will protect DNA from oxidative damage in vivo, Big Blue((R)) mice were fed either a control diet (66 IU vitamin E/kg diet) or a high-dose vitamin E diet containing 1000 IU vitamin E/kg diet of racemic d,l-alpha-tocopherol acetate from conception until 3...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.