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Article

Spontaneous tandem-base mutations (TBM) show dramatic tissue, age, pattern and spectrum specificity.

Mutation research - 10 Jan 2003

Hill Kathleen A, Wang Jicheng, Farwell Kelly D, Sommer Steve S

Abstract excerpt

To supplement a previous analysis of spontaneous tandem-base mutations (TBM) in the lacI gene of Big Blue((R)) mice, 2658 additional mutants were sequenced from 13 tissues and 44 spontaneous TBM were identified (tripling the sample size). Previous findings were confirmed and generalized and several new observations were made. TBM differ from single and other double mutations in that TBM frequency varies...

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PMID: 12504766
DOI: 10.1016/s1383-5718(02)00277-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Spontaneous tandem-base mutations (TBM) show dramatic tissue, age, pattern and spectrum specificity.PMID 12504766Read ↗

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