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Article

Prognostic significance of p53 gene mutations and p53 protein expression in synovial sarcomas.

Virchows Archiv : an international journal of pathology - 1 Oct 1999

Schneider-Stock R, Onnasch D, Haeckel C, Mellin W, Franke D S, Roessner A

Abstract excerpt

Alterations to p53 seem to be of prognostic significance in soft tissue sarcomas, but their significance for synovial sarcomas has not been studied. We analysed 34 synovial sarcomas in 19 patients for p53 alterations (p53 gene mutations + p53 immunopositivity) and examined this factor for its prognostic value in a group of 15 primary tumours. DNA was prepared from paraffin-embedded tumour material by a modified...

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Identifiers

PMID: 10526004
DOI: 10.1007/s004280050418

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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