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Article

Properties of spin and fluorescent labels at a receptor-ligand interface.

Biophysical journal - 1 Oct 1999

Owenius R, Osterlund M, Lindgren M, Svensson M, Olsen O H, Persson E, Freskgård P O, Carlsson U

Abstract excerpt

Site-directed labeling was used to obtain local information on the binding interface in a receptor-ligand complex. As a model we have chosen the specific association of the extracellular part of tissue factor (sTF) and factor VIIa (FVIIa), the primary initiator of the blood coagulation cascade. Different spectroscopic labels were covalently attached to an engineered cysteine in position 140 in sTF, a position...

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Identifiers

PMID: 10512843
DOI: 10.1016/S0006-3495(99)77064-5
PMCID: PMC1300504

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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