Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sequential coagulation factor VIIa domain binding to tissue factor.

Biochemical and biophysical research communications - 2 Dec 2005

Osterlund Maria, Persson Egon, Carlsson Uno, Freskgård Per-Ola, Svensson Magdalena

Abstract excerpt

Vessel wall tissue factor (TF) is exposed to blood upon vascular damage which enables association with factor VIIa (FVIIa). This leads to initiation of the blood coagulation cascade through localization and allosteric induction of FVIIa procoagulant activity. To examine the docking pathway of the FVIIa-TF complex, various residues in the extracellular part of TF (sTF) that are known to interact with FVIIa were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Factor VIIa
Share to Models, Molecular
Share to Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Protein Binding

Share to Protein Structure, Tertiary

Share to Spectrometry, Fluorescence

Share to Thromboplastin

Source

Identifiers

PMID: 16236263
DOI: 10.1016/j.bbrc.2005.09.190

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sequential coagulation factor VIIa domain binding to tissue factor.PMID 16236263Read ↗

Spectroscopic probing of the influence of calcium and the gla domain on the interaction between the first EGF domain in factor VIIa and tissue factor.Semantic proximity Read ↗

Probing the interface between factor Xa and tissue factor in the quaternary complex tissue factor-factor VIIa-factor Xa-tissue factor pathway inhibitor.Semantic proximity Read ↗

Identification of surface residues mediating tissue factor binding and catalytic function of the serine protease factor VIIa.Semantic proximity Read ↗

Molecular interaction between factor VII and tissue factor.Semantic proximity Read ↗

Cofactor-induced and mutational activity enhancement of coagulation factor VIIa.Semantic proximity Read ↗

Properties of spin and fluorescent labels at a receptor-ligand interface.Semantic proximity Read ↗

Protein A is the von Willebrand factor binding protein on Staphylococcus aureus.Semantic proximity Read ↗

Four loops of the catalytic domain of factor viia mediate the effect of the first EGF-like domain substitution on factor viia catalytic activity.Semantic proximity Read ↗

Enhancing the anticoagulant potency of soluble tissue factor mutants by increasing their affinity to factor VIIa.Semantic proximity Read ↗

Structure and dynamics of zymogen human blood coagulation factor X.Semantic proximity Read ↗

Investigating the two regimes of fibrin clot lysis: an experimental and computational approachSemantic proximity Read ↗

Rapid-reaction kinetic characterization of the pathway of streptokinase-plasmin catalytic complex formation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.