Article
Genetic polymorphism of drug-metabolizing enzymes and susceptibility to oral cancer.
Carcinogenesis - 1 Oct 1999
Sato M, Sato T, Izumo T, Amagasa T
Abstract excerpt
An individual difference in the susceptibility to chemical carcinogens is one of the most important factors in the estimate of risk of human cancer. Recently, it has been reported that genetic risk for tobacco-related cancers is associated with polymorphisms of the CYP1A1 and GSTM1 genes in terms of genotype frequencies and cigarette smoking dose. In this study, we investigated the inter-individual difference in...
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