Article
Polymorphisms of CYP1A1 and GSTM1 genes and susceptibility to oral cancer.
Yonsei medical journal - 30 Apr 2007
Cha In-Ho, Park Jong Yun, Chung Won-Yoon, Choi Min-Ah, Kim Hyung-Jun, Park Kwang-Kyun
Abstract excerpt
PURPOSE: Oral cancer is the fifth most common form of cancer in the world and comprises 6.5% of all cancer deaths. Since one of the major risk factors for oral cancer is tobacco use, we hypothesized that polymorphic genes coding for tobacco carcinogen-metabolizing enzymes may play a role in oral cancer susceptibility. MATERIALS AND METHODS: To investigate the association between polymorphisms of the CYP1A1 and...
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