Polymorphisms of the CYP1A1 and GSTM1 gene involved in oral squamous cell carcinoma in association with a cigarette dose.

doi:10.1016/s1368-8375(98)00094-3

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Article

Polymorphisms of the CYP1A1 and GSTM1 gene involved in oral squamous cell carcinoma in association with a cigarette dose.

Oral oncology - 1 Mar 1999

Tanimoto K, Hayashi S, Yoshiga K, Ichikawa T

Abstract excerpt

The genetic polymorphisms of CYP1A1 and GSTM1 genes among 100 Japanese patients with oral squamous cell carcinomas (SCC) were investigated to evaluate the role of genetic susceptibility in carcinogenesis of the oral cavity. The presence of the rare homozygote of CYP1A1, m2/m2, was significantly more frequent in the patient group (15.0%) than the control group (8.0%) (Odds ratio (ORs) = 3.6 95% Confidential...

Topics

Adult
Aged
Aged, 80 and over
Alleles
Carcinoma, Squamous Cell
Cytochrome P-450 CYP1A1
Female
Genetic Predisposition to Disease
Genotype
Glutathione Transferase
Homozygote
Humans
Japan
Male
Middle Aged
Mouth Neoplasms
Polymorphism, Genetic
Smoking

Source

Open in PubMed

Identifiers

PMID: 10435155
DOI: 10.1016/s1368-8375(98)00094-3

Genes

GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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