Article
Genetic susceptibility to squamous cell carcinoma of the lung in relation to cigarette smoking dose.
Cancer research - 1 Oct 1991
Nakachi K, Imai K, Hayashi S, Watanabe J, Kawajiri K
Abstract excerpt
Cytochrome P450IA1 is responsible for the metabolic activation of benzo(a)pyrene in cigarette smoke; an association of lung cancer with DNA polymorphisms of P450IA1 gene was shown in our previous study. In this paper, we investigated the interindividual difference of genetically determined susceptibility to squamous cell carcinoma of the lung in relation to cigarette smoking dose. We first compared the total...
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