Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic polymorphism of drug metabolizing enzymes (GSTM1 and CYP1A1) as risk factors for oral premalignant lesions and oral cancer.

Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia - 1 Sept 2012

Shukla Deepika, Dinesh Kale Alka, Hallikerimath Seema, Vivekanandhan Subbiah, Venkatakanthaiah Yerrmalla

Abstract excerpt

AIMS: Polymorphisms in the genes that code for metabolic enzymes involved in either the activation (Phase I) or detoxication (Phase II) of chemical carcinogens in tobacco, may alter expression or function of carcinogenic compounds and hence alter risk of oral cancer. The present study investigates whether polymorphisms at CYP1A1 and GSTM1 gene loci act as risk factors for oral precancerous lesions and cancer....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinogens
Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP1A1

Share to Glutathione Transferase

Share to Mouth Neoplasms

Share to Nicotiana

Share to Polymorphism, Restriction Fragment Length

Share to Precancerous Conditions

Source

Identifiers

PMID: 22660220
DOI: 10.5507/bp.2012.013

Genes

GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic polymorphism of drug metabolizing enzymes (GSTM1 and CYP1A1) as risk factors for oral premalignant lesions and oral cancer.PMID 22660220Read ↗

Polymorphisms of CYP1A1 and GSTM1 genes and susceptibility to oral cancer.Semantic proximity Read ↗

Susceptibility to oral cancer by genetic polymorphisms at CYP1A1, GSTM1 and GSTT1 loci among Indians: tobacco exposure as a risk modulator.Semantic proximity Read ↗

Genetic polymorphism of CYP1A1, GSTM1 and GSTT1 genes in Indian oral cancer.Semantic proximity Read ↗

Combined effect of smoking and polymorphisms in tobacco carcinogen-metabolizing enzymes CYP1A1 and GSTM1 on the head and neck cancer risk in North Indians.Semantic proximity Read ↗

Germline genetic polymorphisms of CYP1A1, GSTM1 and GSTT1 genes in Indian cervical cancer: associations with tumor progression, age and human papillomavirus infection.Semantic proximity Read ↗

Smoking related risk involved in individuals carrying genetic variants of CYP1A1 gene in head and neck cancer.Semantic proximity Read ↗

Interactions between cigarette smoking and polymorphisms of xenobiotic-metabolizing genes: the risk of oral leukoplakia.Semantic proximity Read ↗

Genetic polymorphisms of CYP1A1, CYP2E1, GSTM1, and GSTT1 associated with head and neck cancer.Semantic proximity Read ↗

Genetic variation in carcinogen metabolizing genes associated with oral cancer in pakistani population.Semantic proximity Read ↗

Association of CYP1A1 and GSTM1 Polymorphisms With Oral Cancer Susceptibility: A Meta-Analysis.Semantic proximity Read ↗

CYP1A1 and GSTM1 polymorphisms and oral cancer risk: association studies via evidence-based meta-analyses.Semantic proximity Read ↗

Role of cytochrome P-450 genetic polymorphisms in oral carcinogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.