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Article

Increased susceptibility to carcinogen-induced mammary tumors in MMTV-Cdc25B transgenic mice.

Oncogene - 16 Sept 1999

Yao Y, Slosberg E D, Wang L, Hibshoosh H, Zhang Y J, Xing W Q, Santella R M, Weinstein I B

Abstract excerpt

Cdc25 phosphatases activate cyclin-dependent kinases (Cdks) by dephosphorylating critical phospho-tyrosine and phospho-threonine residues on these proteins. Several types of studies indicate that Cdc25s can enhance cell proliferation and oncogenesis. Furthermore, overexpression of Cdc25A and/or B have been detected in several types of primary human cancers, including breast cancers. To further assess the...

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Share to 9,10-Dimethyl-1,2-benzanthracene
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Viral

Share to Mammary Neoplasms, Experimental

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Share to Mice, Inbred CBA

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Source

Identifiers

PMID: 10498865
DOI: 10.1038/sj.onc.1202908

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Increased susceptibility to carcinogen-induced mammary tumors in MMTV-Cdc25B transgenic mice.PMID 10498865Read ↗

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