Article
Normal cell cycle and checkpoint responses in mice and cells lacking Cdc25B and Cdc25C protein phosphatases.
Molecular and cellular biology - 1 Apr 2005
Ferguson Angela M, White Lynn S, Donovan Peter J, Piwnica-Worms Helen
Abstract excerpt
The Cdc25 family of protein phosphatases positively regulates cell division by activating cyclin-dependent protein kinases (CDKs). In humans and rodents, there are three Cdc25 family members--denoted Cdc25A, Cdc25B, and Cdc25C--that can be distinguished based on their subcellular compartmentaliza...
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