Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Overexpression of Cdc25B, an androgen receptor coactivator, in prostate cancer.

Oncogene - 6 Feb 2003

Ngan Elly S W, Hashimoto Yoshihiro, Ma Zhi-Qing, Tsai Ming-Jer, Tsai Sophia Y

Abstract excerpt

Cdc25B is a dual-specific phosphatase that mediates cell cycle progression by activating the cyclin-dependent kinases. It has been shown to possess oncogenic potential. To elucidate its potential contribution to human prostate cancer development, the expression profile of Cdc25B protein in human patients was analysed by immunohistocytochemistry. Cdc25B is frequently overexpressed in human prostate cancer tissues...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to cdc25 Phosphatases
Share to Cell Cycle Proteins
Share to Cell Transformation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunohistochemistry

Share to Prostatic Neoplasms

Share to Receptors, Androgen

Share to Transcription, Genetic

Share to Up-Regulation

Source

Identifiers

PMID: 12569365
DOI: 10.1038/sj.onc.1206121

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Overexpression of Cdc25B, an androgen receptor coactivator, in prostate cancer.PMID 12569365Read ↗

CDCA5 promotes the progression of prostate cancer by affecting the ERK signalling pathwaySemantic proximity Read ↗

In Vivo Roles of CDC25 Phosphatases: Biological Insight into the Anti-Cancer Therapeutic TargetsSemantic proximity Read ↗

CDC25B induces cellular senescence and correlates with tumor suppression in a p53-dependent mannerSemantic proximity Read ↗

Cyclin D1b variant influences prostate cancer growth through aberrant androgen receptor regulationSemantic proximity Read ↗

Overexpression of CDCA8 Predicts Poor Prognosis and Promotes Tumor Cell Growth in Prostate CancerSemantic proximity Read ↗

Cell Cycle Control by the CDC25 PhosphatasesSemantic proximity Read ↗

Restoration of cyclin D2 has an inhibitory potential on the proliferation of LNCaP cells.Semantic proximity Read ↗

CtBP2 modulates the androgen receptor to promote prostate cancer progression.Semantic proximity Read ↗

Knockdown of spindle pole body component 25 homolog inhibits cell proliferation and cycle progression in prostate cancerSemantic proximity Read ↗

CUL4B/miR‐33b/C‐MYC axis promotes prostate cancer progressionSemantic proximity Read ↗

Human Prostatic Acid Phosphatase: Structure, Function and RegulationSemantic proximity Read ↗

Deleted in Breast Cancer 1, a Novel Androgen Receptor (AR) Coactivator That Promotes AR DNA-binding ActivitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.