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Article

Allelic exclusion of the T cell receptor alpha-chain: developmental regulation of a post-translational event.

Seminars in immunology - 1 Oct 1999

Gascoigne N R, Alam S M

Abstract excerpt

Allelic exclusion of the alpha and beta chains of the T cell receptor is maintained by different mechanisms. Exclusion of the beta-chain is primarily by allowing the successful rearrangement of only one of the two beta-chain loci. In the case of the alpha-chain, rearrangement on both chromosomes is very common, as is expression of alpha-chain mRNA and protein encoded by both loci. For the most part, however,...

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Source

Identifiers

PMID: 10497088
DOI: 10.1006/smim.1999.0190

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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