Exclusion and inclusion of alpha and beta T cell receptor alleles.

doi:10.1016/0092-8674(92)90453-j

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Article

Exclusion and inclusion of alpha and beta T cell receptor alleles.

Cell - 1 May 1992

Borgulya P, Kishi H, Uematsu Y, von Boehmer H

Abstract excerpt

Exclusion and inclusion of T cell receptor (TCR) genes were analyzed in alpha beta TCR transgenic mice. Both transgenes are expressed unusually early on the surface of CD4-8-, HSA+, IL-2R- thymocytes. These progenitor cells give rise to progeny, which at the single-cell level contains endogenous...

Topics

Alleles
Animals
Base Sequence
DNA-Binding Proteins
Flow Cytometry
Gene Expression
Gene Rearrangement, alpha-Chain T-Cell Antigen Receptor
Gene Rearrangement, beta-Chain T-Cell Antigen Receptor
Genes
Homeodomain Proteins
Mice
Mice, Inbred C57BL

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Transgenic

Molecular Sequence Data

Oligodeoxyribonucleotides

Proteins

RNA, Messenger

Receptors, Antigen, T-Cell, alpha-beta

Source

Open in PubMed

Identifiers

PMID: 1316241
DOI: 10.1016/0092-8674(92)90453-j

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1316241-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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