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Article

Exclusion and inclusion of alpha and beta T cell receptor alleles.

Cell - 1 May 1992

Borgulya P, Kishi H, Uematsu Y, von Boehmer H

Abstract excerpt

Exclusion and inclusion of T cell receptor (TCR) genes were analyzed in alpha beta TCR transgenic mice. Both transgenes are expressed unusually early on the surface of CD4-8-, HSA+, IL-2R- thymocytes. These progenitor cells give rise to progeny, which at the single-cell level contains endogenous alpha but not beta TCR-RNA as well as protein, in addition to products encoded by the transgenes. Thus, the surface...

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PMID: 1316241
DOI: 10.1016/0092-8674(92)90453-j

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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