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Article

Functional roles of chromosomes 11 and 17 in the transformation of human breast epithelial cells in vitro.

International journal of oncology - 1 Oct 1999

Yang X, Tahin Q, Hu Y F, Russo I H, Balsara B R, Mihaila D, Slater C, Barrett J C, Russo J

Abstract excerpt

Genomic alterations in primary breast cancer play a role in the initiation and progression of the disease. We have analyzed the molecular events involved in the initiation and progression of the neoplastic process in an in vitro experimental system. Immortalization of human breast epithelial cells (HBEC) is associated with 3:9 translocation, p53 mutation and microsatellite instability (MSI) of chromosomes 11p13,...

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Identifiers

PMID: 10493942
DOI: 10.3892/ijo.15.4.629

Genes

DRD2
MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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