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Article

A novel translocation breakpoint within the BPTF gene is associated with a pre-malignant phenotype.

PloS one - 11 Mar 2010

Buganim Yosef, Goldstein Ido, Lipson Doron, Milyavsky Michael, Polak-Charcon Sylvie, Mardoukh Corine, Solomon Hilla, Kalo Eyal, Madar Shalom, Brosh Ran, Perelman Marina, Navon Roy, Goldfinger Naomi, Barshack Iris, Yakhini Zohar, Rotter Varda

Abstract excerpt

Partial gain of chromosome arm 17q is an abundant aberrancy in various cancer types such as lung and prostate cancer with a prominent occurrence and prognostic significance in neuroblastoma--one of the most common embryonic tumors. The specific genetic element/s in 17q responsible for the cancer-promoting effect of these aberrancies is yet to be defined although many genes located in 17q have been proposed to...

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Share to Antigens, Nuclear
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 17

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Share to Translocation, Genetic

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Source

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Identifiers

PMID: 20300178
DOI: 10.1371/journal.pone.0009657
PMCID: PMC2836376

Genes

BPTF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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