Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Update on the molecular profile of the MDA-MB-453 cell line as a model for apocrine breast carcinoma studies

5 Aug 2011

Abstract excerpt

Apocrine carcinoma of the breast has recently been refined through gene expression profiling. Due to various pathological studies, we compared the results with the MDA-MB-453 breast cancer cell line, a proposed model for apocrine breast carcinoma. The MDA-MB-453 cell line is androgen receptor-positive and `triple-negative' in respect to estrogen receptor-α, progesterone receptor and the Her-2/neu protein...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast Cancer Treatment Studies
Share to Breast Lesions and Carcinomas
Share to Cancer and Skin Lesions

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22121396
DOI: 10.3892/ol.2011.375

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Update on the molecular profile of the MDA-MB-453 cell line as a model for apocrine breast carcinoma studiesPMID 22121396Read ↗

Invasive apocrine carcinoma of the breast: clinicopathologic features and comprehensive genomic profiling of 18 pure triple-negative apocrine carcinomas.Semantic proximity Read ↗

Immunohistochemical and molecular profiling of histologically defined apocrine carcinomas of the breast.Semantic proximity Read ↗

A highly invasive subpopulation of MDA-MB-231 breast cancer cells shows accelerated growth, differential chemoresistance, features of apocrine tumors and reduced tumorigenicity in vivo.Semantic proximity Read ↗

PIK3CA mutation in ER-negative and HER2-positive breast cancer with apocrine differentiation.Semantic proximity Read ↗

Establishment and characterisation of a new tumorigenic cell line with a normal karyotype derived from a human breast adenocarcinomaSemantic proximity Read ↗

Isolation and characterization of a new naturally immortalized human breast carcinoma cell line, KAIMRC1Semantic proximity Read ↗

Identification of molecular apocrine breast tumours by microarray analysis.Semantic proximity Read ↗

Epithelial to mesenchymal transition in human breast epithelial cells transformed by 17beta-estradiol.Semantic proximity Read ↗

Androgen receptor driven transcription in molecular apocrine breast cancer is mediated by FoxA1Semantic proximity Read ↗

EGFR and HER-2/neu expression in invasive apocrine carcinoma of the breast.Semantic proximity Read ↗

Immunohistochemical analysis of apocrine breast lesions. Consistent over-expression of androgen receptor accompanied by the loss of estrogen and progesterone receptors in apocrine metaplasia and apocrine carcinoma in situ.Semantic proximity Read ↗

HER2-positive Apocrine Carcinoma of the Breast: A population-based Analysis of Treatment and OutcomeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.