Article
Interactions between detoxifying enzyme polymorphisms and susceptibility to cancer.
IARC scientific publications - 1 Jan 1999
Fryer A A, Jones P W
Abstract excerpt
Many case-control studies on the role of detoxifying enzyme polymorphisms in susceptibility to cancer have identified significant associations, though few have identified effects with sufficient strength to be useful clinically. Odds ratios of 2-3 are the usual finding. Therefore, combinations of risk alleles are increasingly studied in the hope of identifying haplotypes with sufficient biological impact (odds...
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