Article
Genetic susceptibility to environmental toxicants: the interface between human and experimental studies in the development of new toxicological concepts.
Toxicology letters - 28 Feb 2002
Thier Ricarda, Golka Klaus, Brüning Thomas, Ko Yon, Bolt Hermann M
Abstract excerpt
The growing knowledge of the genetic polymorphisms of enzymes metabolising xenobiotics in humans and their connections with individual susceptibility towards toxicants has created new and important interfaces between human epidemiology and experimental toxicology. The results of molecular epidemiological studies may provide new hypotheses and concepts, which call for experimental verification, and experimental...
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