Article
[Combined effects of genetic polymorphisms in cytochrome P450s and GSTM1 on lung cancer susceptibility].
Zhonghua yi xue za zhi - 20 Nov 2007
Gu Yan-Fei, Zhang Zong-De, Zhang Shu-Cai, Zheng Su-Hua, Jia Hong-Yan, Gu Shu-Xiang
Abstract excerpt
OBJECTIVE: To investigate the relationship between the gene polymorphism of metabolizing enzymes and the genetic susceptibility to lung cancer as well as to study the synergistic effects between smoking and the genes. METHODS: Peripheral blood samples were collected from 279 patients with primary lung cancer and 684 age-, nationality-, and native place-matched controls, including patients with benign diseases and...
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