Article
Interactive potential of genetic polymorphism in Xenobiotic metabolising and DNA repair genes for predicting lung cancer predisposition and overall survival in North Indians.
Mutation research. Genetic toxicology and environmental mutagenesis - 1 Feb 2018
Bhardwaj Apurva, Bahl Charu, Sharma Siddharth, Singh Navneet, Behera Digamber
Abstract excerpt
INTRODUCTION: Cancer, a multi-step, multifactorial and multi-gene disease, not only damages the genomic integrity of the cell but also hinders the DNA repair mechanisms of the body. Gene-gene and gene environment interactions amongst the genetic polymorphisms together modulate the susceptibility towards a cancer. We have studied the high order gene interactions between the genetic polymorphism of detoxifying...
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