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Article

Genetic polymorphisms of drug-metabolizing enzymes and lung cancer susceptibility.

Pharmacogenetics - 1 Jan 1995

Kawajiri K, Watanabe J, Eguchi H, Hayashi S

Abstract excerpt

A close association of smoking-associated lung cancer incidence with the Msp 1 and 1le-Val polymorphisms of CYP1A1 gene was found in a Japanese population in terms of genotype frequency comparison and cigarette dose response. A synergistic increase in susceptibility to lung cancer was observed when the susceptible genotypes of CYP1A1 were combined with a deficient GSTM1 genotype. Individual difference in...

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Source

Identifiers

PMID: 7581493
DOI: 10.1097/00008571-199512001-00004

Genes

GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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